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Forecasting Healthy Futures Hosts 3rd Annual Summit in Rio de Janeiro, Brazil ahead of COP30
Rio de Janeiro, Brazil, April 10, 2025— Ahead of COP30 in Belém, Brazil, Forecasting Healthy Futures hosted its third annual Global Summit in Rio de Janeiro to urge action in climate change and health financing, and surface some of the most pressing challenges and promising pathways forward to protect health in a changing climate.
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Climate Change & Health: A Discussion with Derek Wallace, President of Takeda's Global Vaccine Business Unit
In a discussion with Forecasting Healthy Futures, Derek Wallace, president of Takeda’s Global Vaccine Business Unit, talks using science to better tackle the health impacts of climate change.
What are some of the ways that you see climate change impacting human health?
WALLACE: Climate change may have profound impacts on global health. For example, intensifying weather has the potential to disrupt food and water supply, posing a significant risk to nutrition. As the world continually warms, we’re seeing vector populations present for longer periods each year, increasing vector-borne disease all over the world. Imagine someone living in or travelling to an area where vector-borne disease is common. When they travel to an area without the disease but with the vector, they can seed that disease into the local vector population leading to local outbreaks in areas usually non-endemic to the disease. Historically this has occurred with yellow fever, which is why yellow fever vaccinations are crucial to prevent the reintroduction of the virus in places that are currently free from the disease.
We see similar dynamics with dengue. Local dengue outbreaks occurring in places like southern Florida are the result of somebody who might have travelled from another region bringing dengue to new areas where there are now established mosquito populations. As new areas become more conducive to vector growth, the concern is that we’ll see more diseases spread.
How can we help mitigate the impact of climate change? What role can scientists and researchers play?
WALLACE: First, it’s important to identify which areas are going to be most impacted by climate change and where these vector-borne diseases could expand to. With that said, the solution can’t be a one-size-fits-all approach. For example, climate change could make some areas drier, and thus mosquitoes could be less of an issue in those regions. Other areas, however, could see warmer, wetter climates where mosquitoes will start to thrive. We really need to understand and better predict these changing weather patterns, using better models to identify where the impact on human health could be the greatest.
Then, it’s about building resilience – efforts to control vectors have been used for decades, but alone, haven’t been the most effective in preventing all vector-borne diseases. To promote resilience, we need to do more than just vector control. Education plays a critical role, not only in helping at-risk individuals understand and minimize their exposure to diseases, but also in enhancing healthcare systems’ diagnostic and management capabilities. Engaging healthcare professionals is also going to be critical, to help identify and manage health conditions impacted by climate change.
Lastly, scientific advancements in preventative methods like vaccines play a crucial role in mitigating climate-related health risks, helping protect not just individuals but entire populations. Developing and distributing vaccines takes specialized expertise and collaboration and coordination between public and private sectors is key.
As you’ve been working on vaccines, what lessons have you learned?
WALLACE: To be successful there are two key areas we must consider. First, where vaccination fits in when it comes to tackling the health impacts of climate change, and with that, how do we make vaccines accessible. Second, is how to scale up production and distribution of the vaccine – this is key to help governments reduce the burden of disease for the population.
At Takeda we are taking steps to better prepare for the potential impacts of climate change, particularly when it comes to dengue. We have a plant in Germany that’s part of our efforts to manufacture and distribute our dengue vaccine. We also have a broader global strategy to expand access to the vaccine by working with collaborators, which should accelerate access in endemic areas. One of our manufacturing partners is Biological E. Limited in India, and with their support, our goal is to be able to produce and distribute 100 million doses per year by the end of the decade. We’re also exploring country-level initiatives to transfer technology and build further capacity for manufacturing of our dengue vaccine.
Our dengue vaccine is currently available in more than 25 countries, and we’re also excited about clinical trials underway that will help expand our knowledge about the vaccine, further inform implementation strategy and support launches in new countries in the coming years. We started clinical trials in 2013, but the vaccine itself dates back to the 1980s, which underscores how long and complex the vaccine development process can be. It’s a very large commitment for a company to invest in development and manufacturing long before we’re in a position to have an impact, but it reflects our sense of responsibility to protect public health.
It’s so important to recognize that no one group can do this alone. With constant travel across countries and continents, disease outbreaks in one country can impact other areas, spreading quickly. Coordination must be at scale and cross borders. It also must cross segments of society, including hospitals, industries, ministries of health, environment, finance and so on. It’s a very complex, interconnected world that we live in, and we need to be activated in parallel. If we’re all working separately, we can never really expect to address the issue.

What is needed to move forward to better tackle the health impacts of climate change?
WALLACE: We need public health groups like the World Health Organization and others to stay focused on the impacts of climate change on health – helping advise countries on the best ways to build resilience and anticipate challenges. With that, there is also room for the value the private industry can bring. My hope is that there can be more open discussion about the complexity of these issues and the multiple avenues that can be a part of solutions. We need good science, strong trust and companies working in tandem with governments – and we’re already seeing some of that, which is exciting.
If we are going to truly protect our communities from the health challenges posed by climate change and its impact on vector-borne diseases, bold and collective action is required from all sectors to accelerate efforts. For example, ensuring that we get pricing right, making vaccines and other tools accessible. The best way to provide fair pricing is through public funding and public decision making about who should be prioritized for vaccination. Another example is making sure we have enough vaccine supply available for those who need it, ahead of major outbreaks. Predicting, planning and building capacity is critical.
I’m clearly hopeful about the future, because we have knowledge and experience to help address critical environmental health issues, such as the disease-related impacts of climate change. Plus, we recognize that the well-being of our patients and their communities is inextricably linked to the health of our planet.
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New Report Highlights Private Sector’s Critical Role in Advancing Climate-Resilient Health and Nutrition
Comprehensive analysis spans 10 industry sectors responding to climate-driven health and nutrition challenges
May 15, 2025 (Washington, DC) – A new report released by Forecasting Healthy Futures calls for stronger private sector leadership to address the growing health and nutrition risks posed by climate change. Titled “Private sector engagement on the impacts of climate change on health and nutrition,” the report presents a cross-sectoral analysis of private sector responses to climate-driven health and nutrition challenges. It explores how multinational corporations (MNCs) are getting impacted by and are responding across their operations, workforces, consumers, and the communities in which they operate.
While the analysis reveals many sector-specific impacts, the underlying risks are shared across industries. Rising temperatures, extreme weather events, the spread of infectious diseases, environmental degradation, and growing mental health challenges are increasingly contributing to worker illness, absenteeism, and declining productivity. Consumers are facing disrupted supply chains, leading to increased food and water insecurity and changing consumption patterns. Meanwhile, communities are grappling with weakened infrastructure, displacement, and economic instability – compounding health and social vulnerabilities and impacted business continuity.
In response, corporate response is gaining momentum. MNCs are increasingly adopting adaptation strategies that address both occupational risks and broader public health threats. The report outlines emerging strategies across ten sectors—from climate-resilient product innovations and workplace health programs to community investments and public policy engagement. For example, agriculture firms are promoting sustainable farming and farmer well-being, consumer goods companies are building resilient value chains, and energy and infrastructure firms are reinforcing assets and safeguarding communities. Meanwhile, healthcare and life sciences companies are enhancing preparedness for climate-sensitive diseases, and technology and financial services firms are leveraging data and financial tools to address evolving climate risks.
At the same time, the report emphasizes the importance of addressing both immediate threats—like heat stress and extreme weather—and broader, often less visible health impacts, particularly among vulnerable populations in low- and middle-income countries. Expanding this focus can help ensure long-term community well-being and business resilience.
Businesses are uniquely positioned to integrate adaptation measures that address both environmental and health vulnerabilities. The report identifies four critical enablers for scaling private sector impact: strategic integration, measurable accountability, cross-sector collaboration, and innovative financing. Internally, companies are encouraged to gradually integrate climate and health resilience into core planning and operations, supported by practical measurement frameworks and transparent reporting. Externally, partnerships across governments, industries, investors, and civil society are needed to align standards, pool resources, and unlock new financing mechanisms.
Ultimately, the report highlights the opportunity for private sector leadership to accelerate climate adaptation efforts that protect health and nutrition around the world.
“Climate change is fundamentally altering the global health and nutrition landscape,” said Kelly Willis, who leads Forecasting Healthy Futures. “To lead in this space, we must champion bold leadership, foster partnerships, and invest in solutions that address escalating climate-driven health threats. “This report encourages private sector leaders to consider more holistic and integrated strategies in addressing the interconnected challenges of climate and health.”
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About Forecasting Healthy Futures
Forecasting Healthy Futures is a global coalition of leading organizations committed to mobilizing the political will, financial resources, and innovative solutions needed to protect global health gains from the threats posed by climate change. Visit us at www.forecastinghealthyfutures.org.
ClimateSmart Indonesia Launches Novel AI Public Health Platform to Tackle Climate-Driven Diseases

JAKARTA (May 12, 2025) – As part of a broader effort to build more climate-resilient health systems, ClimateSmart Indonesia recently launched (5/5/2025) the world’s first AI-enabled, dual-capability technology platform for forecasting and responding to climate-sensitive diseases.
Developed by the Institute for Health Modeling and Climate Solutions (IMACS), the Indonesian Collaborative Research and Industrial Innovation in AI (KORIKA), and the Mohamed bin Zayed University of Artificial Intelligence (MBZUAI), the technology platform debuted in Jakarta during the “ClimateSmart Indonesia Innovation Forum” under the auspices of Indonesia’s Ministries of Health, Environment, and Communications and Digital Affairs, and in partnership with the country’s meteorology, climatology, and geophysical agency BMKG. The ClimateSmart Indonesia initiative has been working in partnership with these agencies and other stakeholders over the last two years, to advance climate and health data systems and their application in Indonesia, through a collaborative process with funding from Reaching the Last Mile (RLM) and the Patrick J. McGovern Foundation.
Climate & Health Technological Breakthrough
The technology platform developed under the ClimateSmart Indonesia initiative has two main features representing major advances in public health data systems and technology:
- Digital Twin Indonesia that visually models future climate and weather scenarios, and maps emerging disease hotspots to allow early intervention for prevention and response.
- AI Dashboard that delivers hyperlocal forecasts, real-time alerts, and scenario-based planning tools for public health officials to improve the cost-efficiencies of disease control programs.
With predictive accuracy exceeding 90%, this system can anticipate outbreaks of malaria, dengue fever, leptospirosis, and 4 other climate-sensitive diseases.
An Ecosystem for the Future
The technology platform’s technological innovations include:
- AI-based malaria detection from microscope images research
- Development of a GPT-RAG (Retrieval-Augmented Generation) language model for climate-health policy, combining the capabilities of large language models (LLMs) with retrieval mechanisms to provide contextually relevant and accurate responses.
- A powerful database architecture that integrates climate, health, and demographic data
ClimateSmart Indonesia aims to help the Indonesia Government design and implement a “best in class” early warning and response system (EWARS) to address the growing threat of climate-sensitive diseases and other challenges to public health.
“Indonesia is the ideal location for establishing a regional center of excellence for AI, climate, and health. By harnessing the power of artificial intelligence and advanced data analytics, Indonesia is pioneering innovative approaches to anticipate, adapt to, and mitigate the complex health challenges posed by our changing climate,” said Prof. Dr. Hammam Riza, President of KORIKA. “In the coming weeks, we hope to launch a task force to plan for this center of excellence, which will build on Indonesia’s national ecosystem of innovation, science, and governance, serving as a resource for other countries working toward more climate-resilient health systems.”
The launch of the novel digital technologies by the ClimateSmart Indonesia partners represents a pivotal step in the nation’s use of AI to tackle the dual challenges of climate change and public health. “This is not just a technological milestone; it reflects a strong national commitment to protecting lives today while building a more resilient and sustainable future through innovation and global collaboration,” stated Vice Minister of Komdigi Nezar Patria, M.Sc., MBA.
Speaking at the opening ceremony, the Meteorological, Climatology and Geophysics Agency (BMKG) Chairman Dwikorita Karnawati said the urgency of integrating climate and health data to address escalating disease threats. “Studies show that climate is a significant driver of increased human exposure to various diseases,” she said. “Changes in temperature and rainfall patterns affect exposure to water- and food-borne illnesses, such as salmonella, and vector-borne diseases like Lyme disease.”
“ClimateSmart Indonesia represents a paradigm shift in how we approach climate-sensitive diseases,” said Michael Andreas Purwoadi, Infrastructure Deputy at BMKG. “By integrating climate and health information and harnessing AI for prediction and planning, it enables Indonesia to analyze and address disease risks with unprecedented speed and precision.”
“By integrating climate and health intelligence, Indonesia is setting a global precedent,” said Dr. Setiaji, Chief of the Digital Transformation Office at the Ministry of Health. “Through Satu Sehat and ClimateSmart, we’re defining the future of digital public health.”
“To strengthen the resilience of the health system, we need strong health data and significant investments in early warning systems and surveillance. Accurate data is essential for climate-related disease strategy development,” said Then Suyanti, Director of Environmental Health at the Ministry of Health, representing the Minister of Health Ir. Budi Gunadi Sadikin.
During the event, Kelly Willis, Global Lead of the Forecasting Healthy Futures Consortium, highlighted the role of climate data and AI in predicting and preventing the health impacts of climate change. “Forecasting Healthy Futures has a broader mandate to protect global health gains against climate change’s effects. We work by convening experts and mobilizing funding worldwide to invest in health systems that are vulnerable to climate change, making them more resilient,” she explained.
Dr. Kashik Sarkar, Director of IMACS, emphasized that climate change impacts health in three significant ways: it determines who is affected, where individuals can access services, and how diseases cluster geographically, particularly affecting the most vulnerable populations. He stated, “These dynamics make climate and health information crucial. Unfortunately, climate and health data are still siloed across the globe. As a result, most health systems lack an integrated solution. This is where AI comes in; it can help merge this information.”








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About Forecasting Healthy Futures
Forecasting Healthy Futures is a global coalition of leading health and technology organizations committed to mobilizing the political will, financial resources, and innovative solutions needed to protect global health gains from the threats posed by climate change. Malaria No More convenes and leads the consortium. Forecasting Health Futures’ partners include Reaching the Last Mile, Mohamed Bin Zayed University of Artificial Intelligence, the Global Institute for Disease Elimination (GLIDE), PATH, the Tableau Foundation, IBM’s Weather Company, and the Institute for Health Metrics and Evaluation (IHME). For more information, visit: www.ForecastingHealthyFutures.org.
About Reaching the Last Mile
Reaching the Last Mile (RLM) is a portfolio of global health programs working towards disease elimination that is driven by the personal commitment of His Highness Sheikh Mohamed bin Zayed, President of the United Arab Emirates. The Initiative provides treatment and preventative care in communities that lack access to quality health services, with a specific focus on reaching the last mile of disease elimination. RLM’s mission represents His Highness’s dedication to ending preventable diseases that affect the world’s poorest and most vulnerable communities and helping millions of children and adults live healthy, dignified lives. For more information, visit: https://www.ReachingTheLastMile.com
For media inquiries, please contact: Sharan Sunner | Seven Media, on behalf of Reaching the Last Mile, sharansunner@sevenmedia.ae | +971 (0)55 698 4327
About Mohamed bin Zayed University of Artificial Intelligence (MBZUAI)
MBZUAI is a graduate, research university focused on artificial intelligence, computer science, and digital technologies across industrial sectors. The university aims to empower students, businesses, and governments to advance artificial intelligence as a global force for positive progress. MBZUAI offers various graduate programs designed to pursue advanced, specialized knowledge and skills in artificial intelligence, including computer vision, machine learning, and natural language processing. For more information, please visit www.mbzuai.ac.ae
About KORIKA
KORIKA, Collaborative Research and Industrial Innovation in AI, stands as a pioneering force in advancing the landscape of AI research, development, and innovation within Indonesia. Established in 2021, KORIKA has consistently been at the forefront of catalyzing progress in the field of artificial intelligence. Their dedication to fostering trustworthy AI systems, while respecting the rich cultural and societal values of Indonesia, aligns seamlessly with the nation's ambitious vision of becoming a global innovation powerhouse. KORIKA has become a pivotal hub, bringing together experts, researchers, and industry leaders to collectively drive the growth and application of AI technologies. For more information, please visit: https://korika.id/.

Forecasting Healthy Futures Hosts 3rd Annual Summit in Rio de Janeiro, Brazil ahead of COP30
Rio de Janeiro, Brazil, April 10, 2025— Ahead of COP30 in Belém, Brazil, Forecasting Healthy Futures hosted its third annual Global Summit in Rio de Janeiro to urge action in climate change and health financing, and surface some of the most pressing challenges and promising pathways forward to protect health in a changing climate.
Forecasting Healthy Futures Discusses Scaling Wolbachia Replacement Technology to Block Dengue Transmission with Oxitec CEO, Grey Frandsen
In a discussion with Forecasting Healthy Futures, Oxitec's CEO Grey Frandsen discusses the company’s latest milestone: breaking ground on the world’s largest Wolbachia mosquito facility. As part of Oxitec’s Sparks™ platform, this facility will accelerate the global scale-up of Wolbachia replacement technology, a proven, sustainable method of limiting mosquitoes’ ability to transmit dengue.
Can you tell us about dengue and why Oxitec is working to address this issue specifically?
FRANDSEN: The world is experiencing a dengue crisis. Last year, the World Health Organization highlighted that cases were the highest on record, most likely in the hundreds of millions. Climate change is driving the spread of invasive Aedes aegypti mosquitoes into new territories, and existing tools are failing to keep pace – innovative, climate-resilient, sustainable solutions are urgently needed, at scale, to mitigate the worsening effects of climate change on the spread of dengue.
In forging a path for new mosquito technologies to combat Aedes aegypti, Oxitec has led the way in developing and scaling good mosquitoes to fight disease-spreading mosquitoes. With two decades of innovation, pilots and regulatory approvals, we’re now scaling up two technologies to meet this growing challenge: Friendly™ mosquitoes to suppress Aedes aegypti, and Sparks™ Wolbachia mosquitoes to block dengue transmission.
Oxitec’s Friendly™ technology is highly targeted and effective in reducing biting and disease transfer of mosquitoes in urban environments, serving both public and private customers. Sparks™ Wolbachia mosquitoes will complement this solution, providing an area-wide intervention for governments.

Oxitec just announced it broke ground on the world’s largest Wolbachia mosquito facility in Brazil. Can you tell us more about the facility and why this is significant?
FRANDSEN: Oxitec already operates the world’s biggest mosquito factory, supplying Friendly™ Aedes technology – the world’s first commercially scaled mosquito-base suppression technology – to communities, businesses, schools, hospitals and other customers across Brazil seeking effective mosquito-control.
Now, we’re leveraging our proven infrastructure, advanced manufacturing, and implementation systems into building Brazil’s largest Wolbachia production facility. Wolbachia is already proven to reduce dengue transmission in communities – we’re excited to be playing our part in helping make this solution available to a larger number of communities.
What makes this significant is scale. With this facility, we’ll be able to protect up to 100 million people a year from dengue—just from this one site. And we’re building it in Brazil, a country on the front line of the global dengue crisis, so we can deliver this technology to the communities that need it most, in Brazil and globally, leveraging Oxitec’s global distribution network.
What is Wolbachia Replacement Technology? Is it safe?
Wolbachia Replacement Technology – or WRT – is a natural, safe and proven method that uses mosquitoes carrying the Wolbachia bacterium to reduce the spread of dengue. When these mosquitoes are released into a community, Wolbachia spreads through the mosquito population and blocks the viruses they carry. Over time, this reduces the mosquitoes' ability to transmit disease.
It’s been tested extensively, including in a landmark trial in Indonesia that showed a 77% reduction in dengue cases and an 86% drop in hospitalizations. Regulatory bodies worldwide have reviewed it, and it’s been safely used in many countries.
What’s your hope with scaling WRT?
FRANDSEN: Ultimately, our mission is to protect one billion people from dengue. The science is there. Now the challenge is scale. That’s what the Sparks™ platform aims to achieve – taking a proven technology and building the infrastructure and partnerships to deliver it affordably, at speed, and at scale. Our aim is that, by scaling Wolbachia, we can deliver widespread, lasting impact to communities most vulnerable to dengue, helping address an urgent public health challenge.



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Our Take | Refreshed Goals for the Climate and Health Movement Heading into 2025
As a matter of some urgency, our loosely organized but highly engaged and growing coalition of climate and health advocates needs to know how we answer the questions: What's next? What exactly is it that we want to achieve?

Author: Kelly Willis, Global Lead, Forecasting Healthy Futures Consortium
By now, we’ve all had a chance to absorb the outcomes of COP29 in Azerbaijan and reflect on the gains we’ve made in moving health closer to the center of climate discourse. One of the most significant gains, of course, being the establishment of the Baku COP Presidencies Continuity Coalition for Climate and Health.
As Stefan Anderson wrote for Health Policy Watch, “The coalition’s key achievement… is significant: after decades of fighting, health advocates and WHO officials will no longer have to relitigate the importance of health as a central concern in climate talks.”
Where will we now direct the time and energy we’ve been spending over “decades of fighting”, just trying to get health on the UNFCCC map?
The question reminds me of one Minister of Health Chiponda of Malawi asked a room full of delegates at this year’s United Nations General Assembly in New York, in a meeting convened by the COP28 Presidency. “What next after ‘Health Day’?” she asked, referring to last year’s milestone December 3 event in Dubai. “Is it going to be Health Week? Health Month? What exactly is it that we want to achieve?”
As a matter of some urgency, our loosely organized but highly engaged and growing coalition of climate and health advocates needs to know how we answer that question.
Of course, there is no shortage of worthy climate policy goals to pursue in the interest of global health. We’ll continue to push for integrating health in NDCs and ensuring health indices in the global goal on adaptation. We’ll work to see that health-determinant sectors also adapt and become more resilient. We’ll pursue health co-benefits by promoting mitigation in energy, transport, agriculture, food, and other sectors. We should certainly collaborate to identify further action opportunities in all of these areas.
But maybe a definitive starting point would be to establish a global goal for climate finance to support health adaptation initiatives in developing countries.
For all the disappointment around the grossly inadequate $300B target for climate financing negotiated in Baku last month, we shouldn’t lose sight of the opportunity it affords the sectors that most convincingly make a compelling investment case. I can think of few sectors where those funds could have as much impact as in public health.
How much of that $300B should be used to protect lives from the impact of climate change by addressing worsening climate-sensitive disease? How much of it should be used to build resilient health systems and protect against future impact? To fund early warning and response systems? To improve the underlying health of our most vulnerable populations?
Forecasting Healthy Futures invites more urgent dialogue around refreshed goals for the climate and health movement. It’s one of the things we hope to do in earnest at our next Global Summit, scheduled for April 8 -10 in Rio de Janeiro.
Please reach out to see how you and your organization can be involved in our planning!
Register here to participate in person or virtually at our 2025 Forecasting Healthy Futures Global Summit.

Forecasting Healthy Futures Applauds Historic Baku COP Presidencies Continuity Coalition for Climate and Health, Announces 2025 FHF Summit
Forecasting Healthy Futures (FHF), a global consortium of organizations committed to protecting global health gains from the impact of climate change, is delighted to see the launch of the Baku COP Presidencies Continuity Coalition for Climate and Health announced today at COP29.
Forecasting Healthy Futures Announces 2nd Annual Summit on Climate & Health
Forecasting Healthy Futures, in partnership with Reaching the Last Mile, is pleased to announce its second annual Forecasting Healthy Futures Global Summit to be held 18 to 20 June, 2024 in Baku, Azerbaijan.
New Global Campaign, The Face of Change, Launches Ahead of Historic COP28 Health Day to Tackle the Climate-Driven Health Crisis
Ahead of a historic, first-ever Health Day during the 28th United Nations Conference on Climate Change (COP28) in Dubai, Forecasting Healthy Futures—in partnership with TIME CO2—announces the launch of a bold and ambitious global campaign - The Face of Change - that centers health as the human face of climate change. With a focus on real and relatable stories, proven, ready-to-scale solutions and open-source creative content to amplify and activate, the campaign aims to inspire a global movement to save millions of lives today from the direct health impacts of climate change while protecting the health of billions of others by accelerating action to arrest global warming.